We describe Glyptothorax intonsus, a new species of sisorid catfish from the Nam Mang watershed in the Mekong River drainage of Laos. The new species is distinguished from all Mekong drainage Glyptothorax by a combination of its very long nasal barbels, head and body proportions, features of the thoracic adhesive apparatus and lateral line, colouration and body tuberculation.

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